GSK840

GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 0.9 nM, and inhibits kinase activity with an IC50 of 0.3 nM.


Cat. No.: EX-A8526	Purity: >98%

	Chemical structure of GSK840

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	400	In-stock
250mg	600	In-stock
500mg	850	In-stock
1g	1250	In-stock
5g	3750	In-stock
10g	5625	In-stock

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Synonyms	GSK'840
CAS No.	2361146-30-5
Purity	>98%
Formula	C21H23N3O3
Mol Weight	365.4256
Color	White to yellow
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014 Nov 20;56(4):481-95.
CoA	CoA of GSK840

Smiles:	O=C(OC(C)(C)C)CC1=CC=C(N2C3=CC=C(C(NC)=O)C=C3N=C2)C=C1


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