GSK717

GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells.


Cat. No.: EX-A4662	Purity: >98%

	Chemical structure of GSK717

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	875	In-stock
500mg	get quote	In-stock
1g	get quote	In-stock
5g	get quote	5 weeks
10g	get quote	5-6 weeks

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CAS No.	1595278-21-9
Purity	>98%
Formula	C28H28N4O2
Mol Weight	452.5475
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Rickard DJ, et al. Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway. PLoS One. 2013;8(8):e69619. Published 2013 Aug 1.
CoA	CoA of GSK717

Smiles:	O=C(NC1=CC=C2C(CCC2)=C1)CN3C4=CC=CC=C4N=C3CCN(C)C(C5=CC=CC=C5)=O


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