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Product Information:

GSK3685032

GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM.

Cat. No.: EX-A5484    Purity: >98%
Chemical
Chemical structure of GSK3685032


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg617in_stock
250mg1036in_stock
500mg1333in_stock
1g1935in_stock
5g5248in_stock
10g8217in_stock


SynonymsGSK-3685032
CAS No.2170137-61-6
Purity>98%
FormulaC22H24N6OS
Mol Weight420.531
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Pappalardi MB, et al. Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer. 2021;2(10):1002-1017.

CoACoA of GSK3685032
Smiles:N#CC1=C(SC(C2=CC=CC=C2)C(N)=O)N=C(N3CCC(CC3)N)C(C#N)=C1CC

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