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Product Information:

GSK3527497

GSK3527497 is an orally active TRPV4 inhibitor. GSK3527497 is applicable for the research of heart failure .

Cat. No.: EX-A10749    Purity: >98%
Chemical
Chemical structure of GSK3527497


For research only, Do not use for Human!

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CAS No.2215855-22-2
Purity>98%
FormulaC17H16ClFN4O4S
Mol Weight426.85
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Brooks CA, et al. Discovery of GSK3527497: A Candidate for the Inhibition of Transient Receptor Potential Vanilloid-4 (TRPV4). J Med Chem. 2019;62(20):9270-9280.

CoACoA of GSK3527497
Smiles:O([C@@H]1[C@@](CN)(O)CN(S(=O)(=O)C2=CC=C(Cl)C=N2)C1)C3=CC(F)=C(C#N)C=C3

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