GSK3 Peptide Substrate

GSK3β-peptide is a substrate mimetic peptide of glycogen synthase kinase 3-β (GSK3-β) that can bind to the active site of GSK3-β and mimic the behavior of a real substrate. GSK3β-peptide can be used to develop substrate mimetic inhibitors of Akt as potential anticancer drugs .


Cat. No.: EX-A10562	Purity: >98%

	Chemical structure of GSK3 Peptide Substrate

For research only, Do not use for Human!

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Synonyms	GSK3β-peptide
Synonyms 2	Glycyl-L-arginyl-L-prolyl-L-arginyl-L-threonyl-L-threonyl-L-seryl-L-phenylalanyl-L-alanyl-L-glutamic acid
CAS No.	496856-73-6
Purity	>98%
Formula	C47H76N16O16
Mol Weight	1121.2039
Color	White to off-white
State	Solid
Storage	Powder -20°C, sealed storage, away from moisture, 1 year; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Kayser, et al. "Modifications of the GSK3β substrate sequence to produce substrate-mimetic inhibitors of Akt as potential anti-cancer therapeutics." Bioorganic & medicinal chemistry letters 17.7 (2007): 2068-2073.
CoA	CoA of GSK3 Peptide Substrate

Smiles:	C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)C)=O)=O)CO)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CCCNC(=N)N)(=O)[C@H]2N(C([C@H](CCCNC(=N)N)NC(CN)=O)=O)CCC2


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