background


Product Information:

GSK3-IN-10

GSK3-IN-10 (Compound 4) is a multi-target inhibitor, that mainly targets GSK3α and GSK3β with IC50 of 1.0 nM and 2.0 nM. GSK3-IN-10 inhibits the activation of β-catenin, promotes the neuronal survival, and exhibits a protective effect against endoplasmic reticulum stress .

Cat. No.: EX-A16133    Purity: >98%
Chemical
Chemical structure of GSK3-IN-10


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mgget quoteInquire
500mgget quoteInquire
1gget quoteInquire


CAS No.844441-56-1
Purity>98%
FormulaC17H18F2N4O3
Mol Weight364.3466
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ong HW, et al., Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS Chem Neurosci. 2023 May 3;14(9):1672-1685.

CoACoA of GSK3-IN-10
Smiles:O=C(NCC1CCOCC1)C2=NNC=C2NC(=O)C=3C(F)=CC=CC3F

KEYWORDS: buy GSK3-IN-10 | GSK3-IN-10 supplier | purchase | cost | manufacturer | order | distributor | buy 844441-56-1 | 844441-56-1 supplier