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Product Information:

GSK2894631A

HPGDS inhibitor 2 is a highly potent and selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with an IC50 of 9.9 nM.

Cat. No.: EX-A3084    Purity: >98%
Chemical
Chemical structure of GSK2894631A


For research only, Do not use for Human!

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CAS No.2101626-26-8
Purity>98%
FormulaC20H24F2N2O3
Mol Weight378.413
Colorwhite to off-white
Statepowder
SolubilityDMSO >100 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Deaton DN, et al. The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors. Bioorg Med Chem. 2019 Apr 15;27(8):1456-1478.
CoACoA of GSK2894631A
Smiles:FC(F)OC1=CC=C2C(N=CC(C(N[C@@H]3CC[C@@H](C(C)(C)O)CC3)=O)=C2)=C1

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