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Product Information:

GSK199

GSK199 is a reversible and selective PAD4 inhibitor with an IC50 of 200 nM in the absence of calcium.

Cat. No.: EX-A4807    Purity: 98+%
Chemical
Chemical structure of GSK199


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg562In-stock
250mg825In-stock
500mg1225In-stock
1g1925In-stock
5g6648In-stock


CAS No.1549811-53-1
Purity98+%
FormulaC24H29ClN6O2
Mol Weight468.979
Colorlight yellow to yellow
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lewis HD, et al. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat Chem Biol. 2015 Mar;11(3):189-91.

CoACoA of GSK199
Smiles:CCN1C(=CC2=C1N=CC=C2)C3=NC4=C(N3C)C(=CC(=C4)C(=O)N5CCC[C@H](C5)N)OC.Cl

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