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Product Information:

GSK0660

GSK0660 is a potent antagonist of PPARβ and PPARδ, with IC50s of 155 nM for both isoforms.

Cat. No.: EX-A768    Purity: >98%
Chemical
Chemical structure of GSK0660


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg585In-stock
250mg850In-stock
500mg1185In-stock
1g1585In-stock
5g4650In-stock
10g7440In-stock


CAS No.1014691-61-2
Purity>98%
FormulaC19H18N2O5S2
Mol Weight418.487
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Shearer BG, et al. Identification and characterization of a selective peroxisome proliferator-activated receptor beta/delta (NR1C2) antagonist. Mol Endocrinol. 2008 Feb;22(2):523-9. Epub 2007 Nov 1.

[2]. Zhong X, et al. Bezafibrate enhances proliferation and differentiation of osteoblastic MC3T3-E1 cells via AMPK and eNOS activation. Acta Pharmacol Sin. 2011 May;32(5):591-600.

[3]. Lee WJ, et al. Activation of PPARδ attenuates neurotoxicity by inhibiting lipopolysaccharide-triggered glutamate release in BV-2 microglial cells. J Cell Biochem. 2018 Feb 1.

CoACoA of GSK0660
Smiles:COC(=O)C1=C(C=CS1)S(=O)(=O)NC1=CC=C(NC2=CC=CC=C2)C=C1OC

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