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Product Information:

GSK-3β inhibitor 20

GSK-3β inhibitor 20 (compound 3A) is an potent inhibitor of GSK-3β with an IC50 value of 74.4 nM.

Cat. No.: EX-A12824    Purity: >98%
Chemical
Chemical structure of GSK-3β inhibitor 20


For research only, Do not use for Human!

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CAS No.3044109-48-7
Purity>98%
FormulaC22H21N5O2S
Mol Weight419.499
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ning Yan, et al. Design, synthesis and biological evaluation of thieno[3,2-c]pyrazol-urea derivatives as potent glycogen synthase kinase 3β inhibitors based on the DFG-out conformation. Bioorg Med Chem Lett. 2024 Nov 1:112:129932.

CoACoA of GSK-3β inhibitor 20
Smiles:O=C(NC1=CC=CC=C1)NC2=CC(C3=CC(NN=C4NC(C(C)C)=O)=C4S3)=CC=C2

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