GSK-3β inhibitor 2

GSK-3β inhibitor 2 (Compound 3) is a potent, selective and orally active GSK-3β inhibitor with an IC50 of 1.1 nM. GSK-3β inhibitor 2 can cross the blood-brain barrier. GSK-3β inhibitor 2 has the potential for Alzheimer's disease.


Cat. No.: EX-A10783	Purity: >98%

	Chemical structure of GSK-3β inhibitor 2

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
500mg	635	In-stock
1g	947	In-stock

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CAS No.	1702428-31-6
Purity	>98%
Formula	C14H14N4O3S
Mol Weight	318.351
Color	light yellow to yellow
State	solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sivaprakasam P, et al. Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Bioorg Med Chem Lett. 2015 May 1;25(9):1856-63.
CoA	CoA of GSK-3β inhibitor 2

Smiles:	O=C(C1=C(OC)N=C(C2=CC(NC(C3CC3)=O)=NC=C2)S1)N


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