GSK-3484862

GSK-3484862 is a non-covalent inhibitor for DNA methyltransferase (Dnmt1). GSK-3484862 induces DNA hypomethylation to against cancer. GSK-3484862 mediates dramatic demethylation in murine embryonic stem cells with minimal non-specific toxicity.


Cat. No.: EX-A10338	Purity: >98%

	Chemical structure of GSK-3484862

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	587	in_stock
250mg	943	in_stock
500mg	1311	inquire
1g	1974	in_stock
5g	6108	in_stock
10g	9400	in_stock

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Synonyms	(R)-GSK3482364
CAS No.	2170136-65-7
Purity	>98%
Formula	C19H19N5OS
Mol Weight	365.452
Color	light yellow to yellow
State	solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Keystone Symposia 2019 - Epigenetics and Human Disease [2]. Nathalia Azevedo Portilho, et al. The DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells.
CoA	CoA of GSK-3484862

Smiles:	O=C(N)[C@H](SC1=NC(N(C)C)=C(C#N)C(CC)=C1C#N)C2=CC=CC=C2


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