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Product Information:

GS9620

Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC50 of 291 nM.

Cat. No.: EX-A2065    Purity: >98%
Chemical
Chemical structure of GS9620


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg500In-stock
1g700In-stock
2g1300In-stock
3g1800In-stock
5g2850In-stock
10gget quoteIn-stock


CAS No.1228585-88-3
Purity>98%
FormulaC22H30N6O2
Mol Weight410.5126
Colorwhite to yellow
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Rebbapragada I, et al. Molecular Determinants of GS-9620-Dependent TLR7 Activation. PLoS One. 2016 Jan 19;11(1):e0146835.

[2]. Lanford RE, et al. GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees. Gastroenterology. 2013 Feb 13. pii: S0016-5085(13)00169-8.

[3]. D Tumas, et al. Preclinical Characterization of GS-9620, A Potent and Selective Oral TLR7 Agonist.

CoACoA of GS9620
Smiles:CCCCOC1=NC2=C(NC(=O)CN2CC2=CC(CN3CCCC3)=CC=C2)C(N)=N1

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