GPX4-IN-6

GPX4-IN-6 (Compound C25) is a GPX4 covalent inhibitor with an IC50 value of 0.13 μM. GPX4-IN-6 (Compound C25) can induce ferroptosis for the research of triple-negative breast cancer (TNBC).


Cat. No.: EX-A8577	Purity: >98%

	Chemical structure of GPX4-IN-6

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	400	In-stock
250mg	650	In-stock
500mg	1000	In-stock
1g	1450	In-stock

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CAS No.	2922824-07-3
Purity	>98%
Formula	C18H17BrFNO5
Mol Weight	426.234
Color	White to off-white
State	solid powder
Solubility	DMSO : 50 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Chen T, et al. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2023 Jul 27;66(14):10036-10059.
CoA	CoA of GPX4-IN-6

Smiles:	O=C(CBr)N(C1=CC(OC)=C(F)C(OC)=C1)C2=CC(OCCO3)=C3C=C2


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