GPX4-Activator-1d4

PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator (pEC50=4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts.


Cat. No.: EX-A9448	Purity: >98%

	Chemical structure of GPX4-Activator-1d4

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	785	In-stock
250mg	1285	In-stock
500mg	1785	In-stock
1g	2585	In-stock
5g	get quote

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Synonyms	PKUMDL-LC-101-D04
CAS No.	2143896-83-5
Purity	>98%
Formula	C14H23ClN4O2S2
Mol Weight	378.941
Color	White to off-white
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, sealed storage, away from moisture; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Li C, et al. Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4. J Med Chem. 2019;62(1):266-275.
CoA	CoA of GPX4-Activator-1d4

Smiles:	O=S(C1=CC=C(NC(NC2CCCC2)=S)C=C1)(NCCN)=O.[H]Cl


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