GPS167

GPS167 is a specific small molecule splicing regulator SRSF10 inhibitor, modulates BCLAF1 splicing with IC50 of 2 uM in human colorectal HCT116 cells, directly inhibits CLK1, CLK2 and CLK4, but not SRPK1 and DYRK1A.


Cat. No.: EX-A15013	Purity: >98%

	Chemical structure of GPS167

For research only, Do not use for Human!

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CAS No.	3034312-19-8
Purity	>98%
Formula	C17H13N5OS
Mol Weight	335.383
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Muhammad Sohail, et al. NAR Cancer. 2021 May 25;3(2):zcab019.
CoA	CoA of GPS167

Smiles:	O=C(NC=1C=CC=2NN=CC2C1)C=3N=C(SC3)NC=4C=CC=CC4


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