GPR110 peptide agonist P12

GPR110 peptide agonist P12 is a peptide that acts as a GPR110 agonist. GPR110 peptide agonist P12 can significantly enhance the initial rate of GPR110 stimulated G protein GTPγS binding. GPR110 peptide agonist P12 mimics the action of natural ligands, causing the extracellular domain (ECD) of the GPR110 to dissociate from the seven transmembrane domains (7TM), exposing the β-strand-13/stalk region at the N-terminus of the 7TM domain, which acts as an agonist to activate G protein signaling. GPR110 peptide agonist P12 can be used in the study of developmental disorders and cancers related to GPR110 .


Cat. No.: EX-A10571	Purity: >98%

	Chemical structure of GPR110 peptide agonist P12

For research only, Do not use for Human!

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CAS No.	1778685-49-6
Purity	>98%
Formula	C63H96N12O17S
Mol Weight	1325.572
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Stoveken H M, et al. Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist[J]. Proceedings of the National Academy of Sciences, 2015, 112(19): 6194-6199.
CoA	CoA of GPR110 peptide agonist P12

Smiles:	C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(=O)N2[C@H](C(O)=O)CCC2)[C@@H](C)C)=O)(=O)[C@H]3N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CC=CC=C4)NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)CO)=O)=O)CO)=O)[C@H](CC)C)=O)CC(C)C)=O)CCSC)=O)CO)=O)CCC3


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