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Product Information:

GNE-6640

USP7-IN-8 (example 81) is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM in an Ub-Rho110 assay. USP7-IN-8 shows no activity against USP47 and USP5. USP7-IN-8 has anticancer effects.

Cat. No.: EX-A5163    Purity: >98%
Chemical
Chemical structure of GNE-6640


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg500In-stock
25mg785In-stock
50mg1185


CAS No.2009273-60-1
Purity>98%
FormulaC21H21N3O2
Mol Weight347.4103
ColorOff-white to light yellow
Statesolid powder
SolubilitySoluble in DMSO 83.33 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Robert Blake, et al. Usp7 inhibitor compounds and methods of use. US20160272588A1.
CoACoA of GNE-6640
Smiles:O=C(NC)C1=CC=C(C2=C(CC)C(C3=CC=C(O)C=C3)=C(N)N=C2)C=C1

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