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Product Information:

GNE-3565

GNE-3565 is an arylsulfonamide class NaV1.7 inhibitor with subnanomolar channel blockage and mixed subtype selectivity.GNE-3565 can be used for the research of pain .

Cat. No.: EX-A16703    Purity: >98%
Chemical
Chemical structure of GNE-3565


For research only, Do not use for Human!

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25mgget quote


CAS No.2222537-72-4
Purity>98%
FormulaC25H26ClF4N5O2S
Mol Weight572.018
 
 
Reference:  

[1].Kschonsak M, et al. Cryo-EM reveals an unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors. Elife. 2023;12:e84151. Published 2023 Mar 28.

CoACoA of GNE-3565
Smiles:N([C@@H]1[C@@H](N(C)C)C[C@H](CC1)C2=CC(C(F)(F)F)=CC=C2)C3=C(Cl)C=C(S(NC=4C=CN=CN4)(=O)=O)C(F)=C3

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