background


Product Information:

GMB-805

GMB-805 is a novel potent BCR-Abl PROTAC, inducing degradation and demonstrating in vivo activity.

Cat. No.: EX-A5218    Purity: >98%
Chemical
Chemical structure of GMB-805


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg1885Inquire
25mg3385Inquire


CAS No.2489876-41-5
Purity>98%
FormulaC42H46ClF2N9O7S
Mol Weight894.386
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Burslem GM, et al. Scaffold hopping enables direct access to more potent PROTACs with in vivo activity. Chem Commun (Camb). 2020 Jun 23;56(50):6890-6892.

[2]. Chen X, et al. Mighty mini-PROTACs: an emerging class of degraders. Eur J Med Chem. 2026 Jan 5;301:118202.

CoACoA of GMB-805
Smiles:O=C(NC1=CC=C(OC(F)(Cl)F)C=C1)C2=CN=C(NCCOCC(N[C@@H](C(C)(C)C)C(N3[C@H](C(NCC4=CC=C(C5=C(C)N=CS5)C=C4)=O)C[C@@H](O)C3)=O)=O)C(C6=CC=NN6)=C2

KEYWORDS: buy GMB-805 | GMB-805 supplier | purchase | cost | manufacturer | order | distributor | buy 2489876-41-5 | 2489876-41-5 supplier