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Product Information:

Ginkgolide B

Ginkgolide B (BN-52021), a terpene lactone, is a potent platelet activating factor antagonist. Ginkgolide B protects endothelial cells via the activation of PXR from injuries induced by xeno- and endobiotics. Ginkgolide B can pass through the brain-blood barrier. Ginkgolide B has anti-oxidant, anti-inflammatory, anti-tumor, and anti-apoptotic activity. Ginkgolide B has marked neuroprotective effects against ischemia-induced impairments.

Cat. No.: EX-A6801    Purity: >98%
Chemical
Chemical structure of Ginkgolide B


For research only, Do not use for Human!

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SynonymsBilobalide B
Synonyms 2BN 52051
CAS No.15291-77-7
Purity>98%
FormulaC20H24O10
Mol Weight424.3986
Color White to off-white
Statesolid powder
SolubilitySoluble in DMSO ? 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years, 4°C 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Tao Zhou, et al. Ginkgolide B protects human umbilical vein endothelial cells against xenobiotic injuries via PXR activation. Acta Pharmacol Sin. 2016 Feb;37(2):177-86.

[2]. Pei-Dong Zheng, et al. Ginkgolide B promotes the proliferation and differentiation of neural stem cells following cerebral ischemia/reperfusion injury, both in vivo and in vitro. Neural Regen Res. 2018 Jul;13(7):1204-1211.

CoACoA of Ginkgolide B

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