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Product Information:

Gilteritinib

ASP2215 is a potent FLT3/AXL inhibitor. ASP2215 showed potent antileukemic activity against AML with either or both FLT3-ITD and FLT3-D835 mutations.

Cat. No.: EX-A2775    Purity: >99%
Chemical
Chemical structure of Gilteritinib


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg350In-stock
1g560In-stock
5g1655In-stock
10g2436In-stock
25g3897.6In-stock


SynonymsASP2215
CAS No.1254053-43-4
Purity>99%
FormulaC29H44N8O3
Mol Weight552.7115
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. ASP2215, a novel FLT3/AXL inhibitor: Preclinical evaluation in acute myeloid leukemia (AML). 2014 ASCO Annual Meeting.

[2]. Mori M, et al. Gilteritinib, a FLT3/AXL inhibitor, shows antileukemic activity in mouse models of FLT3 mutated acute myeloid leukemia. Invest New Drugs. 2017 Oct;35(5):556-565.

CoACoA of Gilteritinib
Smiles:CCC1=NC(C(N)=O)=C(NC2=CC(OC)=C(C=C2)N2CCC(CC2)N2CCN(C)CC2)N=C1NC1CCOCC1

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