Gemifloxacin mesylate

Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections.


Cat. No.: EX-A9890A	Purity: >98%

	Chemical structure of Gemifloxacin mesylate

For research only, Do not use for Human!

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Synonyms	SB-265805
Synonyms 2	LB-20304a
CAS No.	210353-53-0
Purity	>98%
Formula	C19H24FN5O7S
Mol Weight	485.487
Color	White to off-white
State	solid
Solubility	DMSO : 100 mg/mL H2O : 50 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture and light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Hong CY. Discovery of gemifloxacin (Factive, LB20304a): a quinolone of a new generation. Farmaco. 2001 Jan-Feb;56(1-2):41-4. [2]. Allen A, Kim I, et al. Multiple-dose pharmacokinetics and tolerability of gemifloxacin administered orally to healthy volunteers. Antimicrob Agents Chemother. 2001 Feb;45(2):540-5. [3]. Erdem M, et al. Ingestion of the anti-bacterial agent, gemifloxacin mesylate, leads to increased gst activity and peroxidation products in hemolymph of Galleria mellonella l. (lepidoptera: pyralidae). Arch Insect Biochem Physiol. 2016 Dec;93(4):202-209.
CoA	CoA of Gemifloxacin mesylate

Smiles:	O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CC(CN)/C(C4)=N/OC)=N3)C1=O)O.CS(=O)(O)=O


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