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Product Information:

Fruquintinib

Fruquintinib (HMPL-013) is a highly potent and selective VEGFR 1/2/3 inhibitor with IC50s of 33, 0.35, and 35 nM, respectively.

Cat. No.: EX-A2262    Purity: >99%
Chemical
Chemical structure of Fruquintinib


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
200mg550In-stock
500mg750In-stock
1g1150In-stock
2g2000In-stock
5g3385In-stock
10g4885In-stock


SynonymsHMPL-013
CAS No.1194506-26-7
Purity>99%
FormulaC21H19N3O5
Mol Weight393.3927
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Sun Q, et al. Discovery of fruquintinib, a potent and highly selective small molecule inhibitor of VEGFR 1, 2, 3 tyrosine kinases for cancer therapy. Cancer Biol Ther. 2014;15(12):1635-45.

CoACoA of Fruquintinib
Smiles:CNC(=O)C1=C(C)OC2=CC(OC3=C4C=C(OC)C(OC)=CC4=NC=N3)=CC=C12

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