FR 122047 hydrochloride

FR122047 (hydrochloride) is a selective and oral active inhibitor of COX-1 with an IC50 of 28 nM. FR122047 hydrochloride has antiplatelet, analgesic and anti-inflammatory effects in vivo[1][2][3].


Cat. No.: EX-A15418	Purity: >98%

	Chemical structure of FR 122047 hydrochloride

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	622	in-stock
250mg	1050	in-stock
500mg	1650	in-stock

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CAS No.	130717-51-0
Purity	>98%
Formula	C23H26ClN3O3S
Mol Weight	459.989
Color	White to light yellow
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Dohi M, et al. The anti-platelet actions of FR122047, a novel cyclooxygenase inhibitor. Eur J Pharmacol. 1993 Oct 19;243(2):179-84. [2]. Ochi T, Motoyama Y, Goto T. The analgesic effect profile of FR122047, a selective cyclooxygenase-1 inhibitor, in chemical nociceptive models. Eur J Pharmacol. 2000 Mar 10;391(1-2):49-54. [3]. Ochi T, Goto T. Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis. Br J Pharmacol. 2002 Feb;135(3):782-8.
CoA	CoA of FR 122047 hydrochloride

Smiles:	CN1CCN(CC1)C(=O)C2=NC(=C(S2)C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC.Cl


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