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Product Information:

FPL 64176

FPL64176, a nondihydropyridine compound, is a potent agonist of L-type Ca2+ channels with an EC50 value of 16 nM.

Cat. No.: EX-A14274    Purity: >98%
Chemical
Chemical structure of FPL 64176


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg550In-stock
250mg798In-stock
500mg1120In-stock
1g1480In-stock


CAS No.120934-96-5
Purity>98%
FormulaC22H21NO3
Mol Weight347.407
ColorWhite to off-white
StateSolid
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture and light; In solvent -20°C, 1 month.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Zheng W, Rampe D, Triggle DJ. Pharmacological, radioligand binding, and electrophysiological characteristics of FPL 64176, a novel nondihydropyridine Ca2+ channel activator, in cardiac and vascular preparations. Mol Pharmacol. 1991 Nov;40(5):734-41.

[2]. Baxter AJ, Dixon J, Ince F, Manners CN, Teague SJ. Discovery and synthesis of methyl 2,5-dimethyl-4-[2- (phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylate (FPL 64176) and analogues: the first examples of a new class of calcium channel activator. J Med Chem.

CoACoA of FPL 64176
Smiles:CC1=C(C(=C(N1)C)C(=O)OC)C(=O)C2=CC=CC=C2CC3=CC=CC=C3

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