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Product Information:

FLT3-IN-33

FLT3-IN-33 (Compound 7r) is a FLT3 inhibitor with an IC50 of 7.82  nM. FLT3-IN-33 has superior anticancer activities against acute myeloid leukemia (AML) cells, such as MV4-11 and MOLM-13 cells. FLT3-IN-33 significantly induces cell apoptosis and inhibits phosphorylation of FLT3 pathways. FLT3-IN-33 can be used for AML and other cancers research .

Cat. No.: EX-A16131    Purity: >98%
Chemical
Chemical structure of FLT3-IN-33


For research only, Do not use for Human!

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CAS No.3035801-67-0
Purity>98%
FormulaC25H36N8O
Mol Weight464.6063
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Du K, et al. Design, Synthesis, and Biological Evaluation of Potent FLT3 Inhibitor for Acute Myeloid Leukemia (AML) Treatment. Drug Dev Res. 2025 Aug;86(5):e70119.

CoACoA of FLT3-IN-33
Smiles:N(C=1C(=CN=C(NCCC)N1)C=2NC=3C(N2)=CC=C(C3)N4CCN(C)CC4)[C@@H]5CC[C@@H](O)CC5

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