FKBP12 PROTAC dTAG-13

FKBP12 PROTAC dTAG-13 (dTAG-13), a PROTAC-based heterobifunctional degrader, is a selective degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 effectively engages FKBP12F36V and CRBN, thereby selectively degrading FKBP12F36V.


Cat. No.: EX-A8733	Purity: >98%

	Chemical structure of FKBP12 PROTAC dTAG-13

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	1550	In-stock
1g	2450	In-stock
2g	get quote
3g	get quote
5g	get quote

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Synonyms	dTAG-13
CAS No.	2064175-41-1
Purity	>98%
Formula	C57H68N4O15
Mol Weight	1049.1676
Color	White to light yellow
State	solid powder
Solubility	DMSO? 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.
CoA	CoA of FKBP12 PROTAC dTAG-13

Smiles:	COC1=CC=C(CC[C@H](C2=C(OCC(NCCCCCCOC3=CC=CC4=C3C(N(C5CCC(NC5=O)=O)C4=O)=O)=O)C=CC=C2)OC([C@@H]6CCCCN6C([C@@H](CC)C7=CC(OC)=C(OC)C(OC)=C7)=O)=O)C=C1OC


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