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Product Information:

FGFR1 inhibitor-2

FGFR1 inhibitor-2 is a FGFR1 inhibitor (IC50 is 4.55 μM in MDA-MB-231 cells). FGFR1 inhibitor-2 can be used for the research of metastatic triple-negative breast cancer.

Cat. No.: EX-A13796    Purity: >98%
Chemical
Chemical structure of FGFR1 inhibitor-2


For research only, Do not use for Human!

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CAS No.2410612-08-5
Purity>98%
FormulaC25H22F5N3O3
Mol Weight507.4525
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ashraf-Uz-Zaman M, et al. Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer. Eur J Med Chem. 2021;209:112866.

CoACoA of FGFR1 inhibitor-2
Smiles:FC(C=C1)=CC=C1C(C2=CC=C(F)C=C2)CCCCNC(NC3=CC=C([N+]([O-])=O)C(C(F)(F)F)=C3)=O

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