Fagomine

Fagomine is a mild glycosidase inhibitor. The Ki of the iminosugar Fagomine is 4.8 μM, 39 μM, and 70 μM for Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast), respectively.


Cat. No.: EX-A16622	Purity: >98%

	Chemical structure of Fagomine

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	692	in-stock
50mg	1136	in-stock
100mg	1998	in-stock

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Synonyms	D-Fagomine
CAS No.	53185-12-9
Purity	>98%
Formula	C6H13NO3
Mol Weight	147.1723
Color	Off-white to yellow
State	solid
Solubility	H2O : ? 36 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Mena-Barragán T, et al. Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp2-iminosugar conjugates againstglycosidases: A structure-activity relationship study in Gaucher fibroblasts. Eur J Med Chem. 2015 Aug 31. pii: S0223-5234(15)30222-1. [2].Ramos-Romero S, et al. Effect of (D)-fagomine on excreted Enterobacteria and weight gain in rats fed a high-fat high-sucrose diet. Obesity (Silver Spring). 2014 Apr;22(4):976-9. [3].Molinar-Toribio E, et al. D-Fagomine attenuates metabolic alterations induced by a high-energy-dense diet in rats. Food Funct. 2015 Aug;6(8):2614-9.
CoA	CoA of Fagomine

Smiles:	C(O)[C@@H]1[C@@H](O)[C@H](O)CCN1


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