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Product Information:

Fadrozole hydrochloride

Fadrozole hydrochloride (CGS 16949A) is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM.

Cat. No.: EX-A2624A    Purity: >98%
Chemical
Chemical structure of Fadrozole hydrochloride


For research only, Do not use for Human!

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500mg700In-stock
1g985In-stock
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SynonymsCGS 16949A
Synonyms 2(Rac)-FAD286 hydrochloride
CAS No.102676-31-3
Purity>98%
FormulaC14H14ClN3
Mol Weight259.734
ColorWhite to off-white
Statesolid
SolubilityDMSO : 100 mg/mL H2O : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Browne LJ, et al. Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease. J Med Chem. 1991 Feb;34(2):725-36.

[2]. Gunson DE, et al. Prevention of spontaneous tumours in female rats by fadrozole hydrochloride, an aromatase inhibitor. Br J Cancer. 1995 Jul;72(1):72-5.

[3]. Morales-Montor J, et al. Inhibition of p-450 aromatase prevents feminisation and induces protection during cysticercosis. Int J Parasitol. 2002 Oct;32(11):1379-87.

CoACoA of Fadrozole hydrochloride
Smiles:N#CC1=CC=C(C2CCCC3=CN=CN23)C=C1.Cl

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