EZH2-IN-19

EZH2-IN-19 (conpound N40) is a potent inhibitor of enhancer of zeste homolog 2 (EZH2) WT, with the IC50 of 0.32 nM. EZH2-IN-19 plays an important role in cancer research.


Cat. No.: EX-A13322	Purity: >98%

	Chemical structure of EZH2-IN-19

For research only, Do not use for Human!

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CAS No.	3026848-13-2
Purity	>98%
Formula	C40H55N7O3
Mol Weight	681.9098
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Di Wu, et al. Discovery of novel pyridone-benzamide derivatives possessing a 1-methyl-2-benzimidazolinone moiety as potent EZH2 inhibitors for the treatment of B-cell lymphomas. Bioorg Med Chem. 2024 May 1:105:117725.
CoA	CoA of EZH2-IN-19

Smiles:	CCN(C1CCC(CC1)N(C)C)C2=CC(C3=CC=C4C(N(C(N4C5CCN(C)CC5)=O)C)=C3)=CC(C(NCC6=C(C=C(NC6=O)C)C)=O)=C2C


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