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Eriodictyol 7-O-glucoside

Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is an Nrf2 activator. Eriodictyol-7-O-glucoside exhibits significant scavenging effects on both hydroxyl radicals and superoxide anions, with IC50 values of 0.28 mM and 0.30 mM, respectively. Eriodictyol-7-O-glucoside increases the nuclear localization of Nrf2 and induces the expression of the Nrf2/ARE-dependent genes. Eriodictyol-7-O-glucoside provides protection against oxygen and glucose deprivation (OGD)-induced oxidative insult. Eriodictyol-7-O-glucoside demonstrates neuroprotective efficacy in a rat model of focal cerebral ischemia (MCAO). Eriodictyol-7-O-glucoside can be used for the study of stroke.

Cat. No.: EX-A6776    Purity: >98%
Chemical
Chemical structure of Eriodictyol 7-O-glucoside


For research only, Do not use for Human!

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CAS No.38965-51-4
Purity>98%
FormulaC21H22O11
Mol Weight450.3928
Color Off-white to light yellow
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, protect from light; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Hu Q, et al. Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity. Food Chem Toxicol. 2012 Jun;50(6):1927-32.

[2]. Jing X, et al. Eriodictyol-7-O-glucoside activates Nrf2 and protects against cerebral ischemic injury. Toxicol Appl Pharmacol. 2013 Dec 15;273(3):672-9.

[3]. Yao H, et al. Antioxidative flavanone glycosides from the branches and leaves of Viscum coloratum. Chem Pharm Bull (Tokyo). 2006 Jan;54(1):133-5.

CoACoA of Eriodictyol 7-O-glucoside

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