Eras-4001

Eras-4001 (Compound 14-1) is a pan-KRAS inhibitor. Eras-4001 has potent antitumor activities and significantly inhibits the proliferation of wild-type and mutant (such as KRASG12D, KRASG12V and KRASG12C) cancer cells. Eras-4001 effectively inhibits tumor growth in GP2D and Panc0403 xenograft mouse models.


Cat. No.: EX-A15517	Purity: >98%

	Chemical structure of Eras-4001

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	970	In-stock
10mg	1575	In-stock
25mg	2968	In-stock
50mg	4980	In-stock

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CAS No.	3024878-19-8
Purity	>98%
Formula	C36H39ClF4N8O3
Mol Weight	743.193
Color	White to off-white
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zhang Y, et al. Heterocyclic substituted pyrimidopyran compound and use thereof. WO2023246914A1. 2023-12-28.
CoA	CoA of Eras-4001

Smiles:	C(OC1=NC(=C2C(=N1)C[C@H](OC2)C3=C(C(F)(F)F)C(C#CC)=CC(N)=C3F)N4CC=5N(CCC4)N=C(C(N(C)C)=O)C5Cl)[C@@]67N(CC(=C)C6)CCC7


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