Inhibitor Specialist 
Product Information:
| Cat. No.: EX-A316 | Purity: >98% |
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| Chemical structure of EPZ5676 |
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| Synonyms | Pinometostat |
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| CAS No. | 1380288-87-8 |
| Purity | >98% |
| Formula | C30H42N8O3 |
| Mol Weight | 562.7063 |
| Color | white to off-white |
| State | powder |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
| Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Reference: | [1]. Klaus CR, et al. DOT1L inhibitor EPZ-5676 displays synergistic antiproliferative activity in combination with standard of care drugs and hypomethylating agents in MLL-rearranged leukemia cells. J Pharmacol Exp Ther. 2014 Sep;350(3):646-56. |
| CoA | CoA of EPZ5676 |
| Smiles: | CC(C)N(C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12)[C@@H]1C[C@H](CCC2=NC3=CC(=CC=C3N2)C(C)(C)C)C1 |
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