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Product Information:

EPZ004777

EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.

Cat. No.: EX-A1764    Purity: >98%
Chemical
Chemical structure of EPZ004777


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg700In-stock
250mg985In-stock
500mg1350In-stock
1g1950Inquire
5g79502 weeks
10g135002 weeks


CAS No.1338466-77-5
Purity>98%
FormulaC28H41N7O4
Mol Weight539.6696
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Daigle SR, et al. Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor. Cancer Cell. 2011 Jul 12;20(1):53-65.

CoACoA of EPZ004777
Smiles:CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC2=C1N=CN=C2N

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