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Product Information:

EPZ-025654

EPZ-025654 is a potent and selective arginine methyltransferase CARM1 inhibitor.

Cat. No.: EX-A9429    Purity: >98%
Chemical
Chemical structure of EPZ-025654


For research only, Do not use for Human!

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SynonymsGSK-35336023
CAS No.1888328-89-9
Purity>98%
FormulaC29H33ClN8O3
Mol Weight577.077
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  1: Drew AE, Moradei O, Jacques SL, Rioux N, Boriack-Sjodin AP, Allain C, Scott MP, Jin L, Raimondi A, Handler JL, Ott HM, Kruger RG, McCabe MT, Sneeringer C, Riera T, Shapiro G, Waters NJ, Mitchell LH, Duncan KW, Moyer MP, Copeland RA, Smith J, Chesworth R, Ribich SA. Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma. Sci Rep. 2017 Dec 21;7(1):17993. doi: 10.1038/s41598-017-18446-z. PubMed PMID: 29269946; PubMed Central PMCID: PMC5740082.
CoACoA of EPZ-025654
Smiles:O[C@@H](COC1=CC=C(C(C2=NC(C3=C(C)ON=C3C)=C(C)C(N4CC5=NC(N6CCC6)=NC=C5C4)=N2)=C1)Cl)CNC

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