Epmedin C

Epmedin C (Epimedin-C; Baohuoside-VI) is an orally active anti-inflammatory agent and immunomodulator that binds to multiple key proteins including UCP1, Caspase-1, CDK2 and Keap1. Epmedin C inhibits epithelial cell proliferation by disrupting the complex function of CDK2/Cyclin E. Epmedin C also upregulates Nrf2 expression, reduces ROS levels and inhibits pro-inflammatory cytokine secretion, thereby effectively restoring antibody production and alleviating tissue damage. Epmedin C has good safety with no hepatotoxicity or skin sensitization, and it has been used in studies on diseases such as obesity, Deoxynivalenol-induced immunotoxicity and mammary hyperplasia.


Cat. No.: EX-A6785	Purity: >98%

	Chemical structure of Epmedin C

For research only, Do not use for Human!

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Synonyms	Baohuoside VI
CAS No.	110642-44-9
Purity	>98%
Formula	C39H50O19
Mol Weight	822.8029
Color	Light yellow to yellow
State	solid powder
Solubility	Soluble in DMSO 250 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years, 4°C 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zhou HR, et al. Jinlida Granules Reduce Obesity in db/db Mice by Activating Beige Adipocytes. Biomed Res Int. 2022;2022:4483009. Published 2022 May 19. [2]. Bu W, et al. Epmedin C Alleviates Deoxynivalenol-Induced Immunotoxicity by Inhibiting Caspase-1 Activation in Chicken Macrophages. J Agric Food Chem. 2025;73(37):23617-23632. [3]. Zheng M, et al. Ruhe Sanjie Tablet ameliorates depression-associated mammary gland hyperplasia by modulating estrogen receptor signaling and CDK2. J Ethnopharmacol. 2026;359:121025. [4]. Huang Z, et al. Virtual Screening of Kelch-like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Inhibitors and In Vitro Validation. Molecules. 2025;30(8):1815. Published 2025 Apr 17.
CoA	CoA of Epmedin C


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