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Product Information:

Eperezolid

Eperezolid(PNU-100592) is a oxazolidinone antibacterial agent with spectra of activity against antibiotic-susceptible and -resistant gram-positive pathogens.

Cat. No.: EX-A5272    Purity: >98%
Chemical
Chemical structure of Eperezolid


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg550In-stock
50mg850In-stock
100mg1285In-stock
200mg1885In-stock


SynonymsPNU-100592
CAS No.165800-04-4
Purity>98%
FormulaC18H23FN4O5
Mol Weight394.3974
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO 40 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Rybak MJ, et al. Comparative in vitro activities and postantibiotic effects of the oxazolidinone compounds eperezolid (PNU-100592) and linezolid (PNU-100766) versus vancomycin against Staphylococcus aureus, coagulase-negative staphylococci, Enterococcus faecalis, and Enterococcus faecium. Antimicrob Agents Chemother. 1998 Mar;42(3):721-4.

[2]. Lin AH, et al. The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin. Antimicrob Agents Chemother. 1997 Oct;41(10):2127-31.

[3]. Zhou CC, et al. 1H nuclear magnetic resonance study of oxazolidinone binding to bacterial ribosomes. Antimicrob Agents Chemother. 2002 Mar;46(3):625-9.
CoACoA of Eperezolid
Smiles:CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCN(CC3)C(=O)CO)F

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