Enfiborole

Enfiborole is an oxaborolane ester inhibitor with trypanocidal activity against parasites. Enfiborole displays IC50 values ≤ 20 nM against Trypanosoma brucei and Trypanosoma cruzi, and its IC50 against replicating trypanosomes ranges from 21 to 999 nM. Enfiborole inhibits the growth of Trypanosoma brucei, suppresses hypoxanthine incorporation in replicating trypanosomes, and inhibits the growth of Trypanosoma cruzi amastigotes. Enfiborole can be used in studies related to trypanosome infections .


Cat. No.: EX-A16894	Purity: >98%

	Chemical structure of Enfiborole

For research only, Do not use for Human!

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CAS No.	2152662-88-7
Purity	>98%
Formula	C21H22BF3N2O5
Mol Weight	450.216
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Akama T, et al. Oxaborole esters and uses thereof. WO2017195069A1. WIPO; 2017 Nov 16.
CoA	CoA of Enfiborole

Smiles:	CC1=C2C(COB2O)=CC=C1C(N[C@@H](C(C)C)C(OCC3=CN=C(C(F)(F)F)C=C3)=O)=O


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