Endovion

Endovion is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor.


Cat. No.: EX-A9098	Purity: >98%

	Chemical structure of Endovion

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	850	In-stock
1g	1500	In-stock
5g	3499	In-stock

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Synonyms	NS3728
CAS No.	265646-85-3
Purity	>98%
Formula	C16H9BrF6N6O
Mol Weight	495.177
Color	White to off-white
State	Solid
Solubility	Soluble in DMSO/H2O
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 year;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sørensen BH, et al. Downregulation of LRRC8A protects human ovarian and alveolar carcinoma cells against CDDP-induced expression of p53, MDM2, p21Waf1/Cip1, and Caspase-9/-3 activation. Am J Physiol Cell Physiol. 2016 Jun 1;310(11):C857-73. [2]. Sauter DR, et al. ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC). Pflugers Arch. 2015 Jul;467(7):1495-1508.
CoA	CoA of Endovion

Smiles:	FC(F)(F)C1=CC(C(F)(F)F)=CC(NC(NC2=C(C3=NN=NN3)C=C(Br)C=C2)=O)=C1


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