EN106

EN106 is a potent inhibitor of FEMIB and is a cysteine-reactive covalent ligand. EN106 disrupts recognition of the key reductive stress substrate of FEM1B, FNIP1.


Cat. No.: EX-A7027	Purity: >98%

	Chemical structure of EN106

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
200mg	550	In-stock
500mg	850	In-stock
1g	1185	In-stock

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CAS No.	757192-67-9
Purity	>98%
Formula	C13H13ClN2O3
Mol Weight	280.707
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 250 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Henning NJ, et al. Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications. J Am Chem Soc. 2022;144(2):701-708. [2]. Zhang W, et al., Glucose-responsive, antioxidative HA-PBA-FA/EN106 hydrogel enhanced diabetic wound healing through modulation of FEM1b-FNIP1 axis and promoting angiogenesis. Bioact Mater. 2023 Jul 22;30:29-45.
CoA	CoA of EN106


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