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Product Information:

Emeramide

Emeramide is a thiol-redox antioxidant and heavy metal chelator .

Cat. No.: EX-A7828    Purity: >98%
Chemical
Chemical structure of Emeramide


For research only, Do not use for Human!

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SynonymsBDTH2
CAS No.351994-94-0
Purity>98%
FormulaC12H16N2O2S2
Mol Weight284.398
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : 100 mg/mL H2O : < 0.1 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Secor JD, et al. Novel lipid-soluble thiol-redox antioxidant and heavy metal chelator, N,N'-bis(2-mercaptoethyl)isophthalamide (NBMI) and phospholipase D-specific inhibitor, 5-fluoro-2-indolyl des-chlorohalopemide (FIPI) attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. Int J Toxicol. 2011 Dec;30(6):619-38.

[2].Patel RB, et al. Thiol-redox antioxidants protect against lung vascular endothelial cytoskeletal alterations caused by pulmonary fibrosis inducer, bleomycin: comparison between classical thiol-protectant, N-acetyl-L-cysteine, and novel thiol antioxidant, N,N'-bis-2-mercaptoethyl isophthalamide. Toxicol Mech Methods. 2012 Jun;22(5):383-96.

[3].Gadde R, et al. N,N'bis-(2-mercaptoethyl) isophthalamide (NBMI) exerts neuroprotection against lead-induced toxicity in U-87 MG cells. Arch Toxicol. 2021 Aug;95(8):2643-2657.

[4].Cheng R, et al. Reversal of genetic brain iron accumulation by N,N'-bis(2-mercaptoethyl)isophthalamide, a lipophilic metal chelator, in mice. Arch Toxicol. 2022 Jul;96(7):1951-1962.

CoACoA of Emeramide
Smiles:SCCNC(=O)C1=CC(=CC=C1)C(=O)NCCS

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