Elsubrutinib

Elsubrutinib (ABBV-105) is an orally active, potent, selective and irreversible Bruton's tyrosine kinase (BTK) inhibitor. The IC50 of Elsubrutinib for BTK catalytic domain is 0.18 μM. Elsubrutinib can be used for the research of inflammatory disease .


Cat. No.: EX-A17497	Purity: >98%

	Chemical structure of Elsubrutinib

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	482	in_stock
100mg	765	in_stock
250mg	1552	in_stock
500mg	2517	in_stock
1g	4030	in_stock
2g	6512	in_stock

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CAS No.	1643570-24-4
Purity	>98%
Formula	C17H19N3O2
Mol Weight	297.3517
Color	White to off-white
State	Solid
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Goess C, et al. ABBV-105, a selective and irreversible inhibitor of Bruton's tyrosine kinase, is efficacious in multiple preclinical models of inflammation [published correction appears in Mod Rheumatol. 2019 May;29(3):v]. Mod Rheumatol. 2019;29(3):510-522.
CoA	CoA of Elsubrutinib

Smiles:	O=C(C1=CC=C([C@H]2CN(C(C=C)=O)CCC2)C3=C1NC=C3)N


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