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Product Information:

ELOVL6 inhibitor Compound B

ELOVL6 inhibitor Compound B is a potent and selective ELOVL6 inhibitor with IC50 of 85 and 38 nM for human and mouse ELOVL6, respectively.

Cat. No.: EX-A8135    Purity: >98%
Chemical
Chemical structure of ELOVL6 inhibitor Compound B


For research only, Do not use for Human!

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CAS No.1135000-36-0
Purity>98%
FormulaC20H20F3N3O3S
Mol Weight439.451
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : ? 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years ; In solvent   -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Shimamura K, Nagumo A, Miyamoto Y, Kitazawa H, Kanesaka M, Yoshimoto R, Aragane K, Morita N, Ohe T, Takahashi T, Nagase T, Sato N, Tokita S. Discovery and characterization of a novel potent, selective and orally active inhibitor for mammalian ELOVL6. Eur J Pharmacol. 2010 Mar 25;630(1-3):34-41. doi: 10.1016/j.ejphar.2009.12.033. Epub 2010 Jan 4. PMID: 20045404.

CoACoA of ELOVL6 inhibitor Compound B
Smiles:O=C(N1C2CC(S(=O)(C3=NC=CC=C3)=O)CC1CC2)NC4=CC=C(C(F)(F)F)C=C4

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