ELOVL6-IN-1

ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner for malonyl-CoA (Ki=994 nM) and palmitoyl-CoA.


Cat. No.: EX-A5167	Purity: >98%

	Chemical structure of ELOVL6-IN-1

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	500	In-stock
25mg	785	In-stock
50mg	1085	In-stock
100mg	1585	In-stock
200mg	2800	In-stock

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CAS No.	1185736-98-4
Purity	>98%
Formula	C27H24F3N3O3
Mol Weight	495.493
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Shimamura K, et al. 5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a potent inhibitor for mammalian elongase of long-chain fatty acids family 6: examination of its potential utility as a pharmacological tool. J Pharmacol Exp Ther. 2009;330(1):249-256.
CoA	CoA of ELOVL6-IN-1

Smiles:	O=C1N(C2=CC=CC=C2)C3=C(C(C(C)(C)CC3)=O)C1(C4=C(C)NN(C5=CC=CC=C5)C4=O)C(F)(F)F


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