ELDKWA

ELDKWA is the highly conserved amino acids on the ecto-domain of gp41. ELDKWA acts as the epitope of a neutralizing monoclonal antibody 2F5 (mAb 2F5) directed against human immunodeficiency virus type 1 .


Cat. No.: EX-A17284	Purity: >98%

	Chemical structure of ELDKWA

For research only, Do not use for Human!

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CAS No.	152051-21-3
Purity	>98%
Formula	C35H52N8O11
Mol Weight	760.8344
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. T Muster, et al. Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS. J Virol. 1994 Jun;68(6):4031-4. [2]. Y Tian, et al. Structure-affinity relationships in the gp41 ELDKWA epitope for the HIV-1 neutralizing monoclonal antibody 2F5: effects of side-chain and backbone modifications and conformational constraints. J Pept Res. 2002 Jun;59(6):264-76.
CoA	CoA of ELDKWA

Smiles:	C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)N)=O)CC(C)C)=O)CC(O)=O)=O)CCCCN)=O)C(N[C@H](C(O)=O)C)=O)C=1C=2C(NC1)=CC=CC2


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