eIF4A3-IN-9

eIF4A3-IN-9 is a Rocaglate analog. eIF4A3-IN-9 interferes with the assembly of the eIF4F translation complex, with EC50 values of 29 and 450 nM against myc-LUC and tub-LUC, respectively. eIF4A3-IN-9 can be used for the research of tumor pathogenesis.


Cat. No.: EX-A11362	Purity: >98%

	Chemical structure of eIF4A3-IN-9

For research only, Do not use for Human!

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CAS No.	1402931-71-8
Purity	>98%
Formula	C28H27NO8
Mol Weight	505.5159
Color	White to off-white
State	solid
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture and light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Liu T, et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J Med Chem. 2012;55(20):8859-8878.
CoA	CoA of eIF4A3-IN-9

Smiles:	COC1=CC=C(C=C1)[C@]23[C@@H]([C@H]([C@H]([C@]2(C4=C(O3)C=C(C=C4OC)C(=O)N)O)O)C(=O)OC)C5=CC=CC=C5


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