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Product Information:

EGFR-IN-81

EGFR-IN-81 (Compound 10i) is an EGFR inhibitor. EGFR-IN-81 inhibits EGFR WT and L858R/T790M with IC50s 4.38 nM and 5.69 nM. EGFR-IN-81 has cytotoxic activity against MCF-7 and HCT116 cells with of 2.07 μM and 6.72 μM respectively.

Cat. No.: EX-A12169    Purity: >98%
Chemical
Chemical structure of EGFR-IN-81


For research only, Do not use for Human!

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CAS No.2968419-65-8
Purity>98%
FormulaC28H24F3N5O4
Mol Weight551.5165
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Cynthia E Theodore, et al. Design, synthesis, anticancer activity and molecular docking of novel 1H-benzo[d]imidazole derivatives as potential EGFR inhibitors. Journal of Molecular Structure. Volume 1294, Part 2, 15 December 2023, 136341.

CoACoA of EGFR-IN-81

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