EED226-COOH

EED226-COOH is an EED226-derived ligand for target protein EED ligand for PROTAC, binds to a ligand for VHL via linker to form UNC6852 to degrade PRC2.


Cat. No.: EX-A8370	Purity: >98%

	Chemical structure of EED226-COOH

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	470	in_stock
500mg	666	in_stock
1g	938	in_stock
2g	1717	in_stock

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CAS No.	2467965-71-3
Purity	>98%
Formula	C17H13N5O3
Mol Weight	335.3168
Color	off-white to light yellow
State	solid powder
Solubility	DMSO : 125 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27(1):47-56.e15.
CoA	CoA of EED226-COOH

Smiles:	O=C(C1=CC=C(C2=CN=C(N3C=NN=C23)NCC4=CC=CO4)C=C1)O


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